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Synthetically-tailored and nature-derived dual COX-2/5-LOX inhibitors: Structural aspects and SAR

Minakshi A. Meshram, Utkarsha O. Bhise, Priyanka N. Makhal, Venkata Rao Kaki

2021European Journal of Medicinal Chemistry66 citationsDOIOpen Access PDF

Topics & Concepts

InflammationCyclooxygenaseArachidonic acidPharmacologyRheumatoid arthritisArachidonate 5-lipoxygenaseChemistryOsteoarthritisArthritisMedicineEnzymeBiochemistryImmunologyPathologyAlternative medicineInflammatory mediators and NSAID effectsSynthesis and biological activityBioactive Compounds and Antitumor Agents
Synthetically-tailored and nature-derived dual COX-2/5-LOX inhibitors: Structural aspects and SAR | Litcius