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Macrophage-targeted immunocytokine leverages myeloid, T, and NK cell synergy for cancer immunotherapy

Michelle von Locquenghien, Pascale Zwicky, Ken Xie, Diego Adhemar Jaitin, Fadi Sheban, Adam Yalin, Florian Uhlitz, Chamutal Gur, Reut Sharet Eshed, Eyal David, Kfir Mazuz, Constanza Marín, Ankita P. Sankar, Devin Mediratta, Roberto Avellino, Assaf Weiner, Ido Amit

2025Cell13 citationsDOI

Topics & Concepts

BiologyCancer researchTumor microenvironmentImmunotherapyImmune systemCytotoxic T cellCancer immunotherapyEffectorImmunologyReprogrammingMyeloidCancerT cellCellImmunityIpilimumabImmune checkpointCancer cellImmunosurveillanceAcquired immune systemMyeloid-derived Suppressor CellMemory T cellCXCR4Innate immune systemLung cancerNatural killer cellImmune cells in cancerAcute Myeloid Leukemia ResearchImmune Cell Function and Interaction
Macrophage-targeted immunocytokine leverages myeloid, T, and NK cell synergy for cancer immunotherapy | Litcius