Synergetic impact of combined navoximod with cisplatin mitigates chemo-immune resistance via blockading IDO1+ CAFs-secreted Kyn/AhR/IL-6 and pol ζ-prevented CIN in human oral squamous cell carcinoma
Feihong Chen, Deming Zhao, Ying Huang, Xin Wen, Shicheng Feng
Topics & Concepts
CisplatinCancer researchImmune systemTumor microenvironmentImmunotherapyMedicineImmunologyChemotherapyInternal medicineTryptophan and brain disordersImmune cells in cancerPolyomavirus and related diseases