Inositols, Probiotics, and Gestational Diabetes: Clinical and Epigenetic Aspects
Ester Vitacolonna, Maria Masulli, Luisa Palmisano, Liborio Stuppia, Marica Franzago
Abstract
There is growing interest in the potential role of different stereoisomers of inositol or their combination as well as probiotics supplementation in healthy glucose metabolism during pregnancy and in promoting offspring health. The aim of this review is to clarify the effects of several inositol and probiotics-based supplements in the prevention and treatment of gestational diabetes (GDM). Moreover, we will discuss the epigenetic aspects and their short- and long-term effects in response to probiotic intervention as well as the possible implications of these findings in guiding appropriate supplementation regimens in pregnancy.
Topics & Concepts
Gestational diabetesPregnancyEpigeneticsOffspringMedicineDiabetes mellitusProbioticType 2 diabetesBioinformaticsGestationPhysiologyEndocrinologyBiologyBiochemistryBacteriaGeneGeneticsGestational Diabetes Research and ManagementInfant Nutrition and HealthBariatric Surgery and Outcomes