Irreversible electroporation combined with PD-L1/IL-6 dual blockade promotes anti-tumor immunity via cDC2/CD4+T cell axis in MHC-I deficient pancreatic cancer
Zhuozhuo Wu, Qungang Shan, Yuyue Jiang, Wei Huang, Ziyin Wang, Ziyin Wang, Yaping Zhuang, Jingjing Liu, Tiankuan Li, Wenlong Yang, Chaojie Li, Tao Wei, Chenlei Wen, Wenguo Cui, Zilong Qiu, Xiaoyu Liu, Zhongmin Wang, Zhongmin Wang
Topics & Concepts
BlockadeElectroporationCancer researchImmunityPancreatic cancerMajor histocompatibility complexCd4 t cellMHC class IMedicineImmunologyImmune systemT cellBiologyCancerInternal medicineReceptorBiochemistryGeneMicrobial Inactivation MethodsCAR-T cell therapy researchImmunotherapy and Immune Responses