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Genetic Screen for Cell Fitness in High or Low Oxygen Highlights Mitochondrial and Lipid Metabolism

Isha H. Jain, Sarah E. Calvo, Andrew L. Markhard, Owen S. Skinner, Tsz‐Leung To, Tslil Ast, Vamsi K. Mootha

2020Cell227 citationsDOIOpen Access PDF

Topics & Concepts

BiologyReactive oxygen speciesGene knockoutGeneMitochondrionCell biologyGenetic screenOxygenPeroxisomeGeneticsPhenotypeOrganic chemistryChemistryMitochondrial Function and PathologyRNA modifications and cancerCancer, Hypoxia, and Metabolism
Genetic Screen for Cell Fitness in High or Low Oxygen Highlights Mitochondrial and Lipid Metabolism | Litcius