CMTM3 Overexpression Predicts Poor Survival and Promotes Proliferation and Migration in Pancreatic Cancer
Zixuan Zhou, Zuyi Ma, Zhenchong Li, Hongkai Zhuang, Chunsheng Liu, Yuanfeng Gong, Shanzhou� Huang, Chuanzhao Zhang, Baohua Hou
Abstract
Background: Recent evidence has shown that CKLF-like MARVEL transmembrane domain containing 3 (CMTM3) promoted carcinogenesis and tumor progression in a variety of cancer types. The goal of our study is to investigate the association between CMTM3 and pancreatic cancer (PC).
Topics & Concepts
Wnt signaling pathwayGene knockdownCancer researchCell growthPancreatic cancerCarcinogenesisBiologyImmunohistochemistrySignal transductionHedgehog signaling pathwayCell migrationCancerCellHedgehogCell cultureImmunologyCell biologyGeneticsCancer Cells and MetastasisPancreatic and Hepatic Oncology ResearchHedgehog Signaling Pathway Studies