Nanosuspensions of a poorly soluble investigational molecule ODM-106: Impact of milling bead diameter and stabilizer concentration
Mayank Singhal, Ana Baumgartner, Elina Turunen, Bert van Veen, Jouni Hirvonen, Leena Peltonen
Topics & Concepts
Particle sizeSolubilityDissolutionWettingFactorial experimentBioavailabilityChemical engineeringMaterials scienceStabilizer (aeronautics)ChromatographyAqueous solutionSodium dodecyl sulfateChemistryOrganic chemistryComposite materialMechanical engineeringMathematicsBioinformaticsBiologyStatisticsEngineeringDrug Solubulity and Delivery SystemsProtein purification and stabilityMicrofluidic and Capillary Electrophoresis Applications