SDF-1α/CXCR4 Pathway Mediates Hemodynamics-Induced Formation of Intracranial Aneurysm by Modulating the Phenotypic Transformation of Vascular Smooth Muscle Cells
Yazhou Yan, Jiachao Xiong, Fengfeng Xu, Chuanchuan Wang, Zhangwei Zeng, Haishuang Tang, Zhiwen Lu, Qinghai Huang
Topics & Concepts
CalponinVascular smooth muscleDownregulation and upregulationHemodynamicsAneurysmVascular remodelling in the embryoPhenotypic switchingMedicinePathologyCell biologyBiologyInternal medicineImmunohistochemistrySurgeryBiochemistryGeneSmooth muscleIntracranial Aneurysms: Treatment and ComplicationsVascular Malformations Diagnosis and TreatmentNeuroinflammation and Neurodegeneration Mechanisms