Microbiota-dependent activation of the myeloid calcineurin-NFAT pathway inhibits B7H3- and B7H4-dependent anti-tumor immunity in colorectal cancer
Kenneth Peuker, Anne Strigli, Daniele V. F. Tauriello, Alexander Hendricks, Witigo von Schönfels, Greta Burmeister, Mario Brosch, Alexander Herrmann, Sandra Krüger, Jessica Nitsche, L Južnić, Marc Marius Geissler, Andreas Hiergeist, André Gessner, Jakob Wirbel, Ruby Priyadarshini Ponnudurai, Antje Tunger, Rebekka Wehner, Daniel E. Stange, Jürgen Weitz, Daniela E. Aust, Gustavo Baretton, Marc Schmitz, Christoph Röcken, Jochen Hampe, Sebastian Hinz, Georg Zeller, Triantafyllos Chavakis, Clemens Schafmayer, Eduard Batlle, Sebastian Zeißig
Topics & Concepts
NFATCalcineurinBiologyCancer researchCD8T cellImmune systemImmunityColorectal cancerCytotoxic T cellImmunologyCancerTransplantationMedicineInternal medicineIn vitroGeneticsBiochemistrySignaling Pathways in DiseasePharmacological Effects of Natural CompoundsImmunotherapy and Immune Responses