Breaking the bond between tetranectin and HMGB1 in sepsis
Cameron W. Paterson, Mandy L. Ford, Craig M. Coopersmith
Abstract
The interaction between tetranectin and high-mobility group box-1 may be manipulated via monoclonal antibodies to improve survival in sepsis (Chen et al ., same issue).
Topics & Concepts
HMGB1High-mobility groupMonoclonal antibodySepsisMedicineImmunologyCell biologyChemistryAntibodyInflammationBiologyBiochemistryGeneAdvanced Glycation End Products researchInflammation biomarkers and pathwaysS100 Proteins and Annexins