Improvement of Rimocidin Biosynthesis by Increasing Supply of Precursor Malonyl-CoA via Over-expression of Acetyl-CoA Carboxylase in Streptomyces rimosus M527
Zhijun Liao, Jinyao Zhang, Yue Shi, Yongyong Zhang, Zheng Ma, Andreas Bechthold, Xiaoping Yu
Topics & Concepts
BiochemistryBiosynthesisBiologyFermentationPyruvate carboxylaseMetabolic engineeringAcetyl-CoA carboxylaseGene expressionEnzymeGeneMicrobial Natural Products and BiosynthesisPlant biochemistry and biosynthesisMicrobial Metabolic Engineering and Bioproduction