Access to α,β-unsaturated carboxylic acids through water-soluble palladium catalyzed hydroxycarbonylation of alkynes using water as the solvent
Jinhe Lv, Lingbo Zong, Jinrong Zhang, Jiaxin Song, Zhao Jinyu, Kai Zhang, Ziqin Zhou, Mingjie Gao, Congxia Xie, Xiaofei Jia, Xinyi Ren
Abstract
A reusable water-soluble Pd(OAc)<sub>2</sub>/sulfoxantphos catalyst has been developed for the hydroxycarbonylation of symmetrical and unsymmetrical alkynes with CO/H<sub>2</sub>O to afford the corresponding α,β-unsaturated carboxylic acids in good yields.
Topics & Concepts
CatalysisPalladiumSolventChemistryWater solubleCarboxylic acidOrganic chemistryCarbon dioxide utilization in catalysisAsymmetric Hydrogenation and CatalysisCatalytic C–H Functionalization Methods