Carrier-free nanoassembly of doxorubicin prodrug and siRNA for combinationally inducing immunogenic cell death and reversing immunosuppression
Senbiao Chen, Dongdong Li, Xiao‐Jiao Du, Xinyu He, Mengwen Huang, Yang Wang, Xianzhu Yang, Jun Wang
Topics & Concepts
DoxorubicinChemoimmunotherapyImmunogenic cell deathProdrugImmunosuppressionSmall interfering RNAGene silencingDrug carrierCancer researchGene knockdownRNA interferenceChemistryImmune systemImmunotherapyPharmacologyDrugMedicineChemotherapyTransfectionImmunologyRNABiochemistryApoptosisSurgeryGeneRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesNanoplatforms for cancer theranostics