Involvement of PI3K/AKT Pathway in the Rapid Antidepressant Effects of Crocetin in Mice with Depression-Like Phenotypes
Susu Lin, Ziwei Chen, Zhaoruncheng Wu, Fei Fei, Zijin Xu, Yingpeng Tong, Wenyu Sun, Ping Wang
Topics & Concepts
CrocetinProtein kinase BAntidepressantPI3K/AKT/mTOR pathwayPharmacologyEndocrinologyGSK-3Internal medicineKinaseChemistryMedicineHippocampusPhosphorylationCrocus sativusSignal transductionBiochemistryTraditional medicineSaffron Plant Research StudiesMedicinal Plants and Bioactive CompoundsTryptophan and brain disorders