Application of omics technologies in dermatological research and skin management
Jianbiao He, Yan Jia
Abstract
BACKGROUND: "Omics" are usually based on the use of high-throughput analysis methods for global analysis of biological samples and the discovery of biomarkers, and may provide new insights into biological phenomena. Over the last few years, the development of omics technologies has considerably accelerated the pace of dermatological research. AIMS: The purpose of this article was to review the development of omics in recent decades and their application in dermatological research. METHODS: An extensive literature search was conducted on omics technologies since the first research on omics. RESULTS: This article summarizes the history and main research methods of the six omics technologies, including genomics, transcriptomics, proteomics, metabolomics, lipidomics, and microbiomics. Their application in certain skin diseases and cosmetics research and development are also summarized. CONCLUSIONS: This information will help to understand the mechanism of some skin diseases and the discovery of potential biomarkers, and provide new insights for skin health management and cosmetics research and development.