Poly(p-coumaric acid) nanoparticles alleviate temporomandibular joint osteoarthritis by inhibiting chondrocyte ferroptosis
Jiaxin Guo, Kai Su, Liying Wang, Bingyu Feng, Xinru You, Miao Deng, Wei Seong Toh, Jun Wu, Bin Cheng, Juan Xia
Abstract
-coumaric acid, that is stable and possess potent antioxidant, anti-inflammatory properties and ferroptosis inhibition, beneficial for treatment of TMJOA.
Topics & Concepts
OsteoarthritisTemporomandibular jointp-Coumaric acidChondrocyteChemistryMaterials scienceOrthodonticsMedicineBiochemistryPathologyIn vitroFerulic acidAlternative medicineOsteoarthritis Treatment and MechanismsExtracellular vesicles in diseaseCancer-related molecular mechanisms research