MLL4 mediates differentiation and tumor suppression through ferroptosis
Shaun Egolf, Jonathan Zou, Amy Anderson, Cory L. Simpson, Yann Aubert, Stephen M. Prouty, Kai Ge, John T. Seykora, Brian C. Capell
Abstract
-mediated tumor suppression, our data uncover a potentially much broader and general role for ferroptosis in the process of differentiation and skin homeostasis.
Topics & Concepts
Cell biologyBiologyChemistryBiophysicsFerroptosis and cancer prognosisRNA modifications and cancerCancer, Lipids, and Metabolism