Iodine-catalyzed thioallylation of indoles using Bunte salts prepared from Baylis–Hillman bromides
Prince Kumar Gupta, Arvind K. Yadav, Anup Sharma, Krishna Nand Singh
Abstract
Metal-free iodine-catalyzed regioselective thioallylation of indoles has been accomplished at room temperature using Bunte salts prepared from Baylis-Hillman bromides. The resulting multi-functional C3 thioallylated indoles exhibit ample structural diversity and good functional group tolerance.
Topics & Concepts
ChemistryIodineCatalysisRegioselectivityOrganic chemistryFunctional groupPolymerSulfur-Based Synthesis TechniquesCatalytic C–H Functionalization MethodsChemical Synthesis and Reactions