TREM2 knockdown improves the therapeutic effect of PD-1 blockade in hepatocellular carcinoma
Qinyu Wang, Kang Zheng, Dong Tan, Gang Liang
Topics & Concepts
Gene knockdownTREM2Cancer researchImmune systemTumor microenvironmentHepatocellular carcinomaBiologyMacrophageImmune checkpointBlockadeImmunotherapyReceptorImmunologyMyeloidCell cultureIn vitroMyeloid cellsGeneticsBiochemistryImmune cells in cancerNeuroinflammation and Neurodegeneration MechanismsImmune Cell Function and Interaction