Carbon–Germanium Bond Formation via Low-Valent Cobalt-Catalyzed Cross-Electrophile Coupling
Haifeng Chen, Chen Zhu, Huifeng Yue, Magnus Rueping
Abstract
An efficient, electrochemically induced cobalt-catalyzed carbon–germanium bond formation provides access to a variety of functionalized germane-containing compounds, including aryl, vinyl, and alkyl germanes. The cobalt-catalyzed germylation is conducted under mild reaction conditions and exhibits a broad scope and functional group tolerance. Mechanistic experimental studies provide insight into the unexpected reaction pathway and the sequential activation of the different electrophiles.
Topics & Concepts
ElectrophileCobaltCatalysisArylChemistryGermaniumCoupling reactionAlkylCombinatorial chemistryCarbon fibersFunctional groupPhotochemistryPalladiumOrganic chemistryMaterials scienceSiliconComposite numberComposite materialPolymerCatalytic Cross-Coupling ReactionsCatalytic C–H Functionalization MethodsOrganoboron and organosilicon chemistry