Interaction of nobiletin with methotrexate ameliorates 7-OH methotrexate-induced nephrotoxicity through endoplasmic reticulum stress-dependent PERK/CHOP signaling pathway
Yurong Song, Linlin Liu, Bin Liu, Rui Liu, Youwen Chen, Chenxi Li, Guangzhi Liu, Zhiqian Song, Cheng Lü, Aiping Lü, Yuanyan Liu
Topics & Concepts
NobiletinNephrotoxicityPharmacologyOxidative stressChemistryEndoplasmic reticulumMetaboliteCHOPUnfolded protein responseMethotrexateKidneyMedicineBiochemistryInternal medicineFlavonoidAntioxidantChemotherapy-induced organ toxicity mitigationRenal Diseases and GlomerulopathiesGarlic and Onion Studies