Blocking P2X4 purinergic receptor attenuates alcohol-related liver fibrosis by inhibiting hepatic stellate cell activation through PI3K/AKT signaling pathway
Zi Xuan Li, Xiao Dong Sheng, Yu Lian Wang, Xiong Lv
Topics & Concepts
Hepatic stellate cellPI3K/AKT/mTOR pathwayProtein kinase BCancer researchHepatic fibrosisSignal transductionReceptorAlcoholic liver diseaseFibrosisAcetaldehydeBiologyPharmacologyChemistryCell biologyMedicineEndocrinologyInternal medicineBiochemistryCirrhosisEthanolLiver physiology and pathologyLiver Disease Diagnosis and TreatmentLiver Disease and Transplantation