Low-dose perfluorooctanoic acid stimulates steroid hormone synthesis in Leydig cells: Integrated proteomics and metabolomics evidence
Qingyu Huang, Lianzhong Luo, Xuejingping Han, Fuping Li, Xi Zhang, Meiping Tian
Topics & Concepts
Perfluorooctanoic acidMetabolomicsHormoneLipid metabolismSteroidogenic acute regulatory proteinChemistrySteroid biosynthesisProteomicsMetabolismBiologySteroid hormoneEndocrinologySteroidMAPK/ERK pathwayLeydig cellReproductive toxicityEndocrine systemMetabolic pathwayInternal medicineToxicityBiochemistrySignal transductionBioinformaticsLuteinizing hormoneGene expressionMedicineGenePer- and polyfluoroalkyl substances researchToxic Organic Pollutants ImpactAir Quality and Health Impacts