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Isoorientin exerts a urate-lowering effect through inhibition of xanthine oxidase and regulation of the TLR4-NLRP3 inflammasome signaling pathway

Meng‐Fei An, Mingyue Wang, Chang Shen, Ze‐Rui Sun, Yun‐Li Zhao, Xuanjun Wang, Jun Sheng

2020Journal of Natural Medicines31 citationsDOI

Topics & Concepts

HyperuricemiaPharmacologyXanthine oxidaseUric acidChemistryInflammasomeIn vivoAllopurinolBiochemistryIsoorientinReceptorBiologyMedicineInternal medicineFlavonoidEnzymeAntioxidantBiotechnologyGout, Hyperuricemia, Uric AcidInflammasome and immune disordersCase Reports on Hematomas
Isoorientin exerts a urate-lowering effect through inhibition of xanthine oxidase and regulation of the TLR4-NLRP3 inflammasome signaling pathway | Litcius