Design of Negative and Positive Allosteric Modulators of the Cannabinoid CB<sub>2</sub> Receptor Derived from the Natural Product Cannabidiol
Gemma Navarro, Ángel González, Adrià Sánchez-Morales, Nil Casajuana-Martín, Marc Gómez-Ventura, Arnau Cordomí, Félix Busquè, Ramón Alibés, Leonardo Pardo, Rafael Franco
Abstract
receptor with potential therapeutic utility.
Topics & Concepts
Allosteric regulationCannabidiolChemistryAllosteric modulatorCannabinoidCannabinoid receptor type 2Partial agonistNatural productMutagenesisStereochemistryCannabinoid receptorAgonistPharmacologyReceptorBiochemistryCannabisBiologyMutationPsychologyGenePsychiatryCannabis and Cannabinoid ResearchReceptor Mechanisms and SignalingPharmacological Receptor Mechanisms and Effects