Glucose biosensors based on Michael addition crosslinked poly(ethylene glycol) hydrogels with chemo-optical sensing microdomains
Tyrell J. Williams, Ananthakrishnan Soundaram Jeevarathinam, Faraz Jivan, Victoria Baldock, Paul Kim, Michael J. McShane, Daniel L. Alge
Abstract
with a difference of just 4.2% variation. The small difference between PEG and alginate embedded sensors indicates that their sensing properties are primarily determined by the glucose sensing microdomains rather than the hydrogel matrix. Overall, the results of this study indicate that Michael addition-crosslinked PEG hydrogels are a promising platform for encapsulation of chemo-optical glucose sensing microdomains.
Topics & Concepts
Self-healing hydrogelsEthylene glycolPEG ratioMaterials scienceCalcium alginateOxygen permeabilityChemical engineeringPolymer chemistryChemistryCalciumOrganic chemistryMetallurgyFinanceOxygenEngineeringEconomicsElectrochemical sensors and biosensorsAnalytical Chemistry and SensorsMicrofluidic and Capillary Electrophoresis Applications