Litcius/Paper detail

Guillain–Barré Syndrome as a Neurological Complication of COVID-19 Infection: A Case Series and Review of the Literature

Hossein Mozhdehipanah, Sepideh Paybast, Reza Gorji

2020International Clinical Neuroscience Journal26 citationsDOIOpen Access PDF

Abstract

The novel coronavirus disease 2019 (COVID-19) is a global pandemic. Although the main clinical manifestations of the COVID-19 infection have confined to the respiratory system, there is some evidence suggesting the neuro-invasive potential of the COVID-19. There are limited reports of Guillain–Barré syndrome (GBS) as a peripheral nervous system complication of COVID-19 infection. We described four patients with COVID-19 infection who developed acute polyneuropathy with a final diagnosis of Guillain–Barré syndrome. COVID-19 may have the potential to invade the peripheral nervous system. GBS, as one of the critical neurological complications of COVID-19, could be considered as a post-infectious event.

Topics & Concepts

Guillain-Barre syndromeMedicineComplicationCoronavirus disease 2019 (COVID-19)PandemicCritical illness polyneuropathyPolyneuropathyPeripheral nervous systemNervous systemSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)DiseaseIntensive care medicinePediatricsCentral nervous systemInfectious disease (medical specialty)Internal medicineCritical illnessCritically illPsychiatryPeripheral Neuropathies and DisordersLong-Term Effects of COVID-19Leprosy Research and Treatment