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RNA polymerase II is required for spatial chromatin reorganization following exit from mitosis

Shu Zhang, Nadine Übelmesser, Nataša Josipović, Giada Forte, Johan A. Slotman, Michael Chiang, Henrike Johanna Gothe, Eduardo Gade Gusmao, Christian Becker, Janine Altmüller, Adriaan B. Houtsmuller, Vassilis Roukos, Kerstin S. Wendt, Davide Marenduzzo, Argyris Papantonis

2021Science Advances122 citationsDOIOpen Access PDF

Abstract

reentry. Our findings reconcile the role of RNAPII in gene expression with that in chromatin architecture.

Topics & Concepts

ChromatinMitosisRNA polymerase IICell biologyBiologyPolymeraseRNA polymeraseRNA polymerase IIIComputational biologyGeneticsRNADNAGeneGene expressionPromoterGenomics and Chromatin DynamicsChromosomal and Genetic VariationsDNA Repair Mechanisms
RNA polymerase II is required for spatial chromatin reorganization following exit from mitosis | Litcius