Facile one-pot multicomponent synthesis of peptoid based gelators as novel scaffolds for drug incorporation and pH-sensitive release
Sharol Sebastian, Eqvinshi Yadav, Priya Bhardwaj, Mulaka Maruthi, Deepak Kumar, Manoj K. Gupta
Abstract
, underscoring the potential of these novel low molecular weight organic gels (LMWOGs) as effective drug delivery systems in the pharmaceutical industry. The gel formulations exhibit biocompatibility and negligible cytotoxicity, as evidenced by cell viability studies conducted using the MTT assay.
Topics & Concepts
Self-healing hydrogelsDrug deliveryCombinatorial chemistryPeptoidAqueous solutionThermal stabilityDrugNanotechnologyChemistryMaterials scienceOrganic chemistryBiochemistryPeptidePsychiatryPsychologyNeuropeptides and Animal PhysiologyChemical Synthesis and AnalysisSupramolecular Self-Assembly in Materials