Characterizations of the Urate Transporter, GLUT9, and Its Potent Inhibitors by Patch-Clamp Technique
Yanyu Chen, Zean Zhao, Yongmei Li, Lu Li, Jiang Yu, Ying Cao, Pingzheng Zhou, Ting Wu, Jianxin Pang
Topics & Concepts
ChemistryUric acidProbenecidPatch clampTransporterBiophysicsInhibitory postsynaptic potentialPharmacologyBiochemistryHEK 293 cellsReceptorInternal medicineBiologyMedicineGeneGout, Hyperuricemia, Uric AcidIon channel regulation and function