Litcius/Paper detail

Mechanisms for target recognition and cleavage by the Cas12i RNA-guided endonuclease

Heng Zhang, Zhuang Li, Renjian Xiao, Leifu Chang

2020Nature Structural & Molecular Biology73 citationsDOIOpen Access PDF

Topics & Concepts

EndonucleaseTrans-activating crRNAGenome editingCRISPRDNABiologyCleavage (geology)RNAComputational biologyCas9Recognition sequenceGenomeGeneticsCell biologyMolecular biologyGeneRestriction enzymePaleontologyFracture (geology)CRISPR and Genetic EngineeringRNA and protein synthesis mechanismsRNA regulation and disease