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Catalytic-dependent and independent functions of the histone acetyltransferase CBP promote pioneer-factor-mediated zygotic genome activation

Audrey J. Marsh, S. A. Pirogov, Yadwinder Kaur, Abby J. Ruffridge, Suresh Sajwan, Tyler J. Gibson, George Hunt, Melissa M. Harrison, Mattias Mannervik

2025Molecular Cell14 citationsDOIOpen Access PDF

Topics & Concepts

BiologyMaternal to zygotic transitionZygoteCell biologyHistone acetyltransferaseHistoneAcetylationGenomeGeneticsGeneEmbryogenesisGenomics and Chromatin DynamicsProtein Degradation and InhibitorsCancer-related gene regulation
Catalytic-dependent and independent functions of the histone acetyltransferase CBP promote pioneer-factor-mediated zygotic genome activation | Litcius