Construction of Pyridine-Based Chiral Ionic Covalent Organic Frameworks as a Heterogeneous Catalyst for Promoting Asymmetric Henry Reactions
Minghui Chen, Jiabin Zhang, Chenxi Liu, Hongrui Li, Hewei Yang, Yaqing Feng, Bao Zhang
Abstract
The difficulties in the separation of products from the reaction mixture and the recovery of the organic cationic ionic liquids (OCILs) catalysts still need to be addressed. Post modification of the pyridine unit in the covalent organic framework (COF) via the formation of pyridinium salts with the chiral bromoacetate led to the chiral ionic COF with OCIL "immobilized", which was utilized as a heterogeneous catalyst for asymmetric Henry reactions with high yield and excellent stereoselectivity.
Topics & Concepts
ChemistryCatalysisPyridineIonic bondingCovalent bondIonic liquidEnantioselective synthesisCombinatorial chemistryOrganic chemistryIonCovalent Organic Framework ApplicationsRadioactive element chemistry and processingInnovative Microfluidic and Catalytic Techniques Innovation