DNASE1L3 as an indicator of favorable survival in hepatocellular carcinoma patients following resection
Shuncong Wang, Haiqing Ma, Xuemin Li, Xiangqiong Mo, Haiyu Zhang, Lewei Yang, Yun Deng, Yan Yan, Guangwei Yang, Xingwei Liu, Huanhuan Sun
Abstract
= 0.134). Multivariate COX analysis revealed that positive DNASE1L3 expression and higher differentiation were significantly associated with better overall survival.This study demonstrated that positive DNASE1L3 expression is an independent prognostic factor for better survival in HCC patients following radical resection.
Topics & Concepts
Hepatocellular carcinomaImmunohistochemistryMalignancyMedicineSurvival analysisProportional hazards modelMultivariate analysisInternal medicineOverall survivalOncologyHepatectomyBlotPathologyProtein expressionCarcinomaSurvival rateBiologyResectionGeneSurgeryBiochemistryAdvanced biosensing and bioanalysis techniquesCancer Genomics and DiagnosticsMicroRNA in disease regulation