Oxygen vacancy healing boosts the piezoelectricity of bone scaffolds
Fangwei Qi, Huixing Li, Xiuwen Gao, Yifeng Wang, Hongyi Qian, Wei Li, Shilin Liu, Huarui Zhou, Shuping Peng, Cijun Shuai
Abstract
. The enhanced piezoelectric current effectively accelerated cell differentiation by upregulating alkaline phosphatase expression, calcium salt deposition and calcium influx. This work provides a novel insight for the design of self-powered stimulation scaffolds for bone regeneration.
Topics & Concepts
ChemistryOxygenBone healingWound healingPiezoelectricityBiophysicsMaterials scienceAnatomyBiologyMedicineSurgeryComposite materialOrganic chemistryBone Tissue Engineering MaterialsAdvanced Sensor and Energy Harvesting Materials3D Printing in Biomedical Research