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Synthesis, molecular modeling simulations and anticancer activity of some new Imidazo[2,1-b]thiazole analogues as EGFR/HER2 and DHFR inhibitors

Esraa A. Moharram, Selwan M. El‐Sayed, Hazem A. Ghabbour, Hussein I. El‐Subbagh

2024Bioorganic Chemistry12 citationsDOI

Topics & Concepts

HeLaChemistryThiazoleIn vivoCell cycle checkpointCell cycleCell cultureIn vitroBiological activityIC50PotencyPharmacologyStereochemistryCellBiochemistryBiologyBiotechnologyGeneticsSynthesis and biological activityClick Chemistry and ApplicationsSynthesis and Characterization of Heterocyclic Compounds
Synthesis, molecular modeling simulations and anticancer activity of some new Imidazo[2,1-b]thiazole analogues as EGFR/HER2 and DHFR inhibitors | Litcius