Designing a high-performance smart drug delivery system for the synergetic co-absorption of DOX and EGCG on ZIF-8
Ahmad Haghi, Heidar Raissi, Hassan Hashemzadeh, Farzaneh Farzad
Abstract
ZIF-8. From the metadynamics simulation, it was found that the geometry of the drugs is a determining factor in an efficient co-loading SDDS.
Topics & Concepts
Drug deliveryvan der Waals forceChemistryImidazoleDrugAdsorptionMolecular dynamicsAbsorption (acoustics)Zeolitic imidazolate frameworkCombinatorial chemistryNanotechnologyStereochemistryComputational chemistryPhysical chemistryMaterials scienceOrganic chemistryMoleculeMetal-organic frameworkPharmacologyMedicineComposite materialMetal-Organic Frameworks: Synthesis and ApplicationsNanoparticle-Based Drug DeliveryMesoporous Materials and Catalysis