Chemical and chemoenzymatic stereoselective synthesis of β-nucleosides and their analogues
Huijing Wang, Yangyang Zhong, You‐Cai Xiao, Fen‐Er Chen
Abstract
β-Nucleosides are fundamental building blocks of biological systems and are used as therapeutic agents for the treatment of cancer and viral infections. This review summarizes the stereoselective synthesis of β-nucleosides and their analogues.
Topics & Concepts
StereoselectivityChemistryCombinatorial chemistryStereochemistryOrganic chemistryCatalysisBiochemical and Molecular ResearchHIV/AIDS drug development and treatmentCarbohydrate Chemistry and Synthesis