Validation of an Accurate and Expedient Initial Rates Method for Characterizing Mechanophore Reactivity
Molly E. McFadden, Anna C. Overholts, Skylar K. Osler, Maxwell J. Robb
Abstract
Understanding structure-mechanochemical reactivity relationships is important for informing the rational design of new stimuli-responsive polymers. To this end, establishing accurate reaction kinetics for mechanophore activation is a key objective. Here, we validate an initial rates method that enables the accurate and rapid determination of rate constants for ultrasound-induced mechanochemical transformations. Experimental reaction profiles are well-aligned with theoretical models, which support that the initial rates method effectively deconvolutes the kinetics of specific mechanophore activation from the competitive process of nonspecific chain scission.
Topics & Concepts
KineticsReactivity (psychology)Chain scissionPolymerMaterials scienceBiological systemReaction rate constantProcess (computing)Chemical kineticsComputer scienceChemical engineeringComposite materialEngineeringPhysicsMedicinePathologyAlternative medicineOperating systemQuantum mechanicsBiologyForce Microscopy Techniques and ApplicationsCellular Mechanics and InteractionsMechanical and Optical Resonators