Differentiated cancer cell-originated lactate promotes the self-renewal of cancer stem cells in patient-derived colorectal cancer organoids
Hui Zhao, Yan Chang, Yibing Hu, Lei Mu, Shuang Liu, Kaiyu Huang, Qilin Li, Xiaolan Li, Deding Tao, Jichao Qin
Topics & Concepts
OrganoidCancerColorectal cancerCancer stem cellCancer researchStem cellCancer cellBiologyMedicineOncologyInternal medicineCell biologyCancer Cells and MetastasisCancer, Hypoxia, and MetabolismEpigenetics and DNA Methylation