Nasal Microbiota Imbalance as a Contributory Link in the Emergence of COVID-19 Associated Mucormycosis
Rachna Singh, Anjna Kumari
Abstract
COVID-19 associated mucormycosis (CAM) is being reported at an elevated frequency and has been declared an ongoing epidemic in India. A huge diabetic population, inappropriate corticosteroid usage and environmental mucoralean spore count, along with COVID-19 associated glycemic imbalance, hypoxemia, increased iron levels, vascular endothelial injury, as well as the immunosuppressive impact are being considered as important risk factors for CAM. The present viewpoint aims to discuss the plausible role of another important facet, the nasal microbiota imbalance, in the emergence of mucormycosis under the prevailing COVID-19 pandemic conditions.
Topics & Concepts
MucormycosisPandemicCoronavirus disease 2019 (COVID-19)PopulationMedicineHypoxemiaIntensive care medicineImmunologyDiseaseEnvironmental healthInternal medicinePathologyInfectious disease (medical specialty)Antifungal resistance and susceptibilityGut microbiota and healthRespiratory and Cough-Related Research