Anti-inflammatory nanoparticles significantly improve muscle function in a murine model of advanced muscular dystrophy

Abstract

recruitment, muscles exhibited increased fiber area and fourfold increases in contraction force and velocity versus controls. The ability of PA4 to shift immune responses, and improve dystrophic muscle function, suggests that immunomodulatory treatment may benefit many genetically diverse muscular dystrophies, all of which share inflammatory pathology.

Topics & Concepts