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Gut bacterial isoamylamine promotes age-related cognitive dysfunction by promoting microglial cell death

Yun Teng, Jingyao Mu, Fangyi Xu, Xiangcheng Zhang, Mukesh K. Sriwastva, Qiaohong M. Liu, Xiaohong Li, Chao Lei, Kumaran Sundaram, Xin Hu, Lifeng Zhang, Juw Won Park, Jae Yeon Hwang, Eric C. Rouchka, Xiang Zhang, Jun Yan, Michael L. Merchant, Huang‐Ge Zhang

2022Cell Host & Microbe135 citationsDOIOpen Access PDF

Topics & Concepts

BiologyTranscription factorCell biologyMicrobiomeNeuroinflammationMyoviridaeTranscriptional regulationRegulatorMicrogliaChromatin immunoprecipitationGenePromoterGeneticsGene expressionImmunologyBacteriophageInflammationEscherichia coliS100 Proteins and AnnexinsGut microbiota and healthAntimicrobial Peptides and Activities
Gut bacterial isoamylamine promotes age-related cognitive dysfunction by promoting microglial cell death | Litcius