Discovery of highly potent and selective VEGFR2 kinase inhibitors for the treatment of rheumatoid arthritis
Qingling Chen, Zhuoying Chen, Feilong Li, Haoyu Zha, Wei He, Fei Jiang, Jiamu Wei, Jiajia Xu, Rong Li, Li Cai, Xuesong Liu, Xuesong Liu
Topics & Concepts
ChemistryAngiogenesisKinomeKinase insert domain receptorPharmacologyArthritisRheumatoid arthritisTyrosine kinaseVascular endothelial growth factorKinaseUmbilical veinCancer researchVascular endothelial growth factor AIn vitroBiochemistrySignal transductionImmunologyVEGF receptorsMedicineAngiogenesis and VEGF in CancerHER2/EGFR in Cancer ResearchNatural Compounds in Disease Treatment