Population Prevalence, Cancer Risk, and Mortality Risk of Turner Syndrome in South Korean Women Based on National Health Insurance Service Data
Sung Eun Kim, Sang Hyun Park, Kyungdo Han, Won Kyoung Cho, Byung‐Kyu Suh, Yong Gyu Park
Abstract
PURPOSE: In South Korea, investigations into Turner syndrome (TS) prevalence and TS-associated cancer and mortality are lacking. Accurate data were estimated from the National Health Insurance Service (NHIS) and the Rare Diseases Registry (RDR) records. MATERIALS AND METHODS: Data on patients with TS who were registered in the RDR between 2007 and 2017 were collected. To estimate TS-associated cancer and mortality risk, the data were compared with data of 1:3 age-matched controls. RESULTS: =0.002). CONCLUSION: National prevalence of TS was suggested, and an increased risk of TS-associated thyroid cancer and mortality were observed in this study.
Topics & Concepts
MedicineDemographyNational health insurancePopulationLifetime riskCancerService (business)Family medicineEnvironmental healthBusinessInternal medicineMarketingSociologyGenetic and Clinical Aspects of Sex Determination and Chromosomal AbnormalitiesThyroid Disorders and TreatmentsHume's philosophy and hair distribution