Photobiomodulation attenuates oligodendrocyte dysfunction and prevents adverse neurological consequences in a rat model of early life adversity
Zhihai Huang, Yulan Zhang, Xiaohui Ma, Yu Feng, Xuemei Zong, J. Dedrick Jordan, Quanguang Zhang
Abstract
Collectively, these findings provide new insights into the mechanism by which ELA affects neurological outcomes. Moreover, our findings support that PBM may be a promising strategy to prevent ELA-induced neurologic sequelae that develops later in life.
Topics & Concepts
OligodendrocyteOxidative stressMedicineAdverse effectPsychologyNeuroscienceInternal medicineMyelinCentral nervous systemLaser Applications in Dentistry and MedicineAnesthesia and Neurotoxicity ResearchSpaceflight effects on biology