One-pot synthesis of a microporous organosilica-coated cisplatin nanoplatform for HIF-1-targeted combination cancer therapy
Xiaojuan Zhang, Chuanchuan He, Xiaoguang Liu, Yan Chen, Pengxuan Zhao, Chen Chen, Ruicong Yan, Minsi Li, Ting Fan, Bouhari Altine, Tan Yang, Yao Lu, Robert J. Lee, Yongkang Gai, Guangya Xiang
Abstract
results suggested that this core-shell nanostructured cisplatin delivery system represented a highly efficacious and promising nanoplatform for the synergistic delivery of combination therapies involving cisplatin.
Topics & Concepts
CisplatinMicroporous materialCancer therapyCancerMaterials scienceCancer researchChemistryNanotechnologyMedicineInternal medicineChemotherapyOrganic chemistryNanoplatforms for cancer theranosticsNanoparticle-Based Drug DeliveryMetal-Organic Frameworks: Synthesis and Applications