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Oxygen-self-supplying biomimetic nanozymes synergize with methotrexate to reprogram macrophage polarization for rheumatoid arthritis therapy

Lingling Lv, Xiaoling Qiu, Weijie Chen, Ziyu Lin, Yating Guo, Longhua Shen, Yanping Deng, Qing Hu

2025Acta Biomaterialia6 citationsDOI

Topics & Concepts

Rheumatoid arthritisArthritisImmune systemMacrophage polarizationInflammationMethotrexateImmunologyReactive oxygen speciesMedicineCancer researchCytokineChemistryOxidative stressInflammatory arthritisChemotaxisSynovial membraneCombination therapyAutoimmunityCerium oxideMacrophagePharmacologyPhotodynamic therapySignal transductionIRF5PathogenesisAdvanced Nanomaterials in CatalysisNanoplatforms for cancer theranosticsNanocluster Synthesis and Applications
Oxygen-self-supplying biomimetic nanozymes synergize with methotrexate to reprogram macrophage polarization for rheumatoid arthritis therapy | Litcius