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Increased expression of ER stress, inflammasome activation, and mitochondrial biogenesis-related genes in peripheral blood mononuclear cells in major depressive disorder

Soumyabrata Munshi, Ahlam M. Alarbi, Haixia Zheng, Rayus Kuplicki, Kaiping Burrows, Leandra K. Figueroa‐Hall, Teresa A. Victor, Robin L. Aupperle, Sahib S. Khalsa, Martin P. Paulus, T. Kent Teague, Jonathan Savitz

2024Molecular Psychiatry23 citationsDOIOpen Access PDF

Topics & Concepts

InflammasomeMitochondrial biogenesisMFN2Unfolded protein responseBiologyTranslocator proteinPeripheral blood mononuclear cellGene expressionMajor depressive disorderEndoplasmic reticulumInflammationImmunologyGeneEndocrinologyMitochondrionCell biologyGeneticsMitochondrial DNAmitochondrial fusionNeuroinflammationIn vitroAmygdalaTryptophan and brain disordersInflammasome and immune disordersEndoplasmic Reticulum Stress and Disease